Anti-CD134, Mouse (OX40) Monoclonal Antibody (Clone: OX-86) BSA/Azide Free
CD134 is a type I integral membrane protein. This receptor is expressed on activated CD4+and CD8+T cells and B cells. The CD134 binds to CD134 ligand (CD252) to provide a costimulatory signal that is independent of CD28. CD134 is involved in coordinating CD4 T cell selection, migration and cytokine differentiation in T helper (Th) 1 and Th2 cells. CD134 is also involved in the stimulation of T cells, T dependent humoral response and generation of optimal CD4+ T cell responses in vivo and in vitro. CD134 is expressed on activated CD4+ T lymphocytes, and its ligand, CD134L, is found preferentially on activated B cells. Engagement of CD134 with its ligand, CD134L, delivers a strong costimulatory signal to effector T cells.
Product Specifications
Product Name Alternative
Gene ID
22163
UniProt
P47741
Host
Rat
Reactivity
Mouse
Immunogen
Purified recombinant Mouse OX-40 antigen
Clonality
Monoclonal
Clone
OX-86
Applications
FACS, IF
Components
1.0 mg/mL of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS
Storage Conditions
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.
Applications Notes
Does not block binding of OX40L; Flow Cytometry (0.5-1ug/million cells in 0.1ml) ; Immunofluorescence (1-2ug/ml)
Isotype
Rat IgG1, kappa
Explore Other Products
Browse additional items from our catalog
TAF13 (Transcription Initiation Factor TFIID Subunit 13, Transcription Initiation Factor TFIID 18kD Subunit, TAF (II) 18, TAFII-18, TAFII18, TAF2K, TAFII18)
