Anti-IL-10R1, Mouse (Interleukin-10 Receptor 1) (CD210) Monoclonal Antibody (Clone: 1B1.3a)
This monoclonal antibody recognizes Mouse Interleukin-10 receptor 1 (IL-10R1), a cell surface glycoprotein of approximately 110KDa. Its epitope is localized in the ligand-binding domain in the extracellular region of Mouse IL-10R1. This antibody blocks the binding of IL-10 to its receptor. IL-10R1 is a class II cytokine receptor expressed on thymocytes, T cells, B cells, NK cells, monocytes and macrophages. Binding of IL-10 to its receptor initiates JAK/STAT signaling that leads to B cell proliferation and inhibition of macrophage activation.
Product Specifications
Product Name Alternative
Gene ID
16154
UniProt
Q61727
Host
Rat
Reactivity
Mouse
Immunogen
Purified recombinant extracellular region of Mouse IL10RA
Clonality
Monoclonal
Clone
1B1.3a
Applications
FACS, IF
Components
Storage Conditions
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.
Applications Notes
Neutralization Studies (Order Ab without Azide) ; Flow Cytometry (0.5-1ug/million cells in 0.1ml) ; Immunofluorescence (1-2ug/ml)
Isotype
Rat IgG1, kappa
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