Anti-IL-10R1, Mouse (Interleukin-10 Receptor 1) (CD210) Monoclonal Antibody (Clone: 1B1.3a)

This monoclonal antibody recognizes Mouse Interleukin-10 receptor 1 (IL-10R1), a cell surface glycoprotein of approximately 110KDa. Its epitope is localized in the ligand-binding domain in the extracellular region of Mouse IL-10R1. This antibody blocks the binding of IL-10 to its receptor. IL-10R1 is a class II cytokine receptor expressed on thymocytes, T cells, B cells, NK cells, monocytes and macrophages. Binding of IL-10 to its receptor initiates JAK/STAT signaling that leads to B cell proliferation and inhibition of macrophage activation.

Product Specifications

Product Name Alternative

CD210 antigen; CDw210a; IBD28; IL10R alpha; IL-10R subunit 1; IL-10R1; IL10RA IL10RIL-10R subunit alpha; interleukin 10 receptor, alpha; interleukin-10 receptor alpha chain; Interleukin-10 receptor subunit 1

Gene ID

16154

UniProt

Q61727

Host

Rat

Reactivity

Mouse

Immunogen

Purified recombinant extracellular region of Mouse IL10RA

Clonality

Monoclonal

Clone

1B1.3a

Applications

FACS, IF

Components

200 μg/mL of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/mL.