Anti-Melanoma Marker (MART-1 + gp100) Monoclonal Antibody (Clone: DT101+ BC199 + HMB45)
Selected Variant
36-3769-100
Size: 100 µg
This antibody cocktail recognizes two melanoma-specific proteins, which include MART-1 and gp100. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Function of gp100 is not known but it is reported to be a useful marker for melanocytes and melanomas. A cocktail of these two markers is sensitive for labeling formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.
Product Specifications
Product Name Alternative
Melanoma antigen recognized by T-cells 1 (MART-1), MLAN-A; PMEL17
Gene Name
MLANA & SILV
Gene ID
2315; 6490
UniProt
Q16655 ; P40967
Host
Mouse
Reactivity
Human
Immunogen
Recombinant hMART-1 protein (DT101 & BC199) ; Extract of pigmented melanoma metastases from lymph nodes (HMB45)
Clonality
Monoclonal
Clone
DT101+ BC199 + HMB45
Applications
IHC
Components
Storage Conditions
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.
Applications Notes
Isotype
Mouse IgG2b, kappa + Mouse IgG1, kappa
Price
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