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Anti-CDw78 Monoclonal Antibody (Clone: DF1588)

Reacts with a carbohydrate determinant, identified as CDw78 (Workshop V; Code CDw78.2) . Epitope recognized by this MAb and Leu21 is the same. It is present on some immature and some peripheral blood B cells, and some B cell lines. Its expression is increased after B-cell activation in vitro. CDw78 is also found on tissue macrophages and on epithelial cells, but not on T cells, NK cells, monocytes, granulocytes and myeloid tissues. It appears that CDw78 is a determinant on a major histocompatibility complex (MHC) class II subpopulation.

Product Specifications

Product Name Alternative

Leu21; Ba antigen; LO panBa

Host

Mouse

Reactivity

Human

Immunogen

Human leucocytes

Clonality

Monoclonal

Clone

DF1588

Applications

Functional Assay, FACS, IF

Components

200 μg/mL of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/mL.

Storage Conditions

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.

Applications Notes

Functional Studies (Order Ab without Azide) ; Flow Cytometry (1-2ug/million cells) ; Immunofluorescence (1-2ug/ml)

Isotype

Mouse IgG1, kappa

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