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Anti-CD3e, Mouse Monoclonal Antibody (Clone: 145-2C11)

CD3 chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex. The 145-2C11 antibody is useful forin vitroblocking and activation assays, as well as apoptosis induction andin vivoT cell depletion.

Product Specifications

Product Name Alternative

CD3 epsilon; CD3e; CD3e antigen epsilon polypeptide (TiT3 complex) ; CD3e molecule, epsilon (CD3-TCR complex) ; IMD18; T-cell surface antigen T3/Leu-4 epsilon chain; T-cell surface glycoprotein CD3 epsilon chain; T3E; TCRE

Gene Name

Cd3e (Mouse)

Gene ID

12501

UniProt

P22646

Host

Hamster

Reactivity

Mouse

Immunogen

H2Kb specific Mouse cytotoxic T lymphocyte clone BM10 37

Clonality

Monoclonal

Clone

145-2C11

Applications

Functional Assay, FACS, IF

Components

200 μg/mL of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/mL.

Storage Conditions

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.

Applications Notes

Functional Studies (Order Antibody without BSA & Azide) ; Flow Cytometry (0.5-1ug/million cells in 0.1ml) ; Immunofluorescence (1-2ug/ml)

Isotype

Armenian Hamster IgG, kappa

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