Anti-CD79b (B-Cell Marker) Monoclonal Antibody (Clone: IGB/1843)
CD79 (also designated Ig chains, designated CD79B or B29. The B cell antigen receptor complex (BCR) is formed by the association of CD79 with a membrane immunoglobulin, such as IgM or IgD. The membrane immunoglobulins IgM and IgD achieve surface expression and antigen presentation function in response to CD79 association. The cytoplasmic tails of both CD79A and CD79B contain an ITAM (immuno-receptor tyrosine-based activation) motif, which acts to initiate the BCR signaling reactions by binding to and activating tyrosine kinases.
Product Specifications
Product Name Alternative
Gene Name
CD79B
Gene ID
974
UniProt
P40259
Host
Mouse
Reactivity
Human
Immunogen
Recombinant human CD79b protein fragment (around aa29-159) (exact sequence is proprietary)
Clonality
Monoclonal
Clone
IGB/1843
Applications
ELISA, WB
Components
Storage Conditions
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.
Applications Notes
ELISA (Use Ab at 2-4ug/ml for coating) (Order Ab without BSA) ; Western Blot (1-2ug/ml)
Isotype
Mouse IgG1, kappa
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