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Anti-CD47 / IAP (Integrin Associated Protein) Monoclonal Antibody (Clone: IAP/964)

This antibody reacts with Ig domain of CD47 protein. CD47, originally named integrin-associated protein (IAP), is a 50kDa protein containing five membrane-spanning sequences and a short cytoplasmic tail. CD47 plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus. CD47 may play a role in membrane transport and/or integrin dependent signal transduction.

Product Specifications

Product Name Alternative

Antigenic Surface Determinant Protein OA3; IAP; Integrin Associated Protein; Integrin Associated Signal Transducer; MER6; OA3; Protein MER6; Rh Related Antigen

Gene Name

CD47

Gene ID

961

UniProt

Q08722

Host

Mouse

Reactivity

Human, Mouse

Immunogen

Recombinant full-length human IAP protein

Clonality

Monoclonal

Clone

IAP/964

Applications

ELISA, Functional Assay, FACS, IF

Components

200 μg/mL of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/mL.

Storage Conditions

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.

Applications Notes

ELISA (For coating, order antibody without BSA) ; , Functional Studies; , Flow Cytometry (1-2ug/million cells) ; , Immunofluorescence (1-2ug/ml) ;

Isotype

Mouse IgG1, kappa

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