Anti-CD6 (Negative Marker of T-regulatory Cells) Monoclonal Antibody (Clone: SPV-L14)
Selected Variant
36-3503-100
Size: 100 µg
CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular scavenger receptor cysteine-rich (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.
Product Specifications
Product Name Alternative
T12; TP120
Gene Name
CD6
Gene ID
923
UniProt
P30203
Host
Mouse
Reactivity
Human, Mouse
Immunogen
CD8+ cytotoxic T-cell clone
Clonality
Monoclonal
Clone
SPV-L14
Applications
FACS, IF
Components
Storage Conditions
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.
Applications Notes
Flow Cytometry (1-2ug/ml) ; , Immunofluorescence (1-2ug/ml) ;
Isotype
Mouse IgG1, kappa
Price
Frequently Asked Questions
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