Anti-CD5 (Mantle Cell Lymphoma Marker) Monoclonal Antibody (Clone: CRIS-1)
Selected Variant
36-3492-100
Size: 100 µg
Recognizes a 67kDa transmembrane protein, which is identified as CD5 (HLDA I; WS Code T 29HLDA III; WS Code T 530) . The CD5 antigen is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. Anti-CD5 is a pan T-cell marker that also reacts with a range of neoplastic B-cells, e.g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), mantle cell lymphoma, and a subset (~10%) of diffuse large B-cell lymphoma. CD5 aberrant expression is useful in making a diagnosis of mature T-cell neoplasms.
Product Specifications
Product Name Alternative
CD5 antigen (p56 62), LEU1, Ly12, LyA, Lymphocyte antigen T1/Leu-1, Lymphocyte glycoprotein T1/Leu1, T-cell surface glycoprotein CD5
Gene Name
CD5
Gene ID
921
UniProt
P06127
Host
Mouse
Reactivity
Human
Immunogen
Stimulated human leukocytes
Clonality
Monoclonal
Clone
CRIS-1
Applications
FACS, IF, Functional Assay, IP
Components
Storage Conditions
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.
Applications Notes
Isotype
Mouse IgG2a, kappa
Price
Frequently Asked Questions
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