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Anti-BCL10 (MALT-Lymphoma Marker) Monoclonal Antibody (Clone: BL10/2988R)

Selected Variant

36-3446-100

Size: 100 µg

BCL10, with an N-terminal caspase recruitment domain (CARD), is found in a number of apoptotic regulatory molecules. It was identified throμgh its direct involvement in t (1;14) of mucosa-associated lymphoid tissue (MALT) lymphoma. Expression of BCL10 was shown to induce NF14) translocation, while 55% of MALT lymphomas lacking this translocation exhibited the same labeling pattern, althoμgh at a much lower level.

Product Specifications

Product Name Alternative

B-cell CLL/lymphoma 10, B-cell leukemia/lymphoma 10, CARD-containing molecule enhancing NF-kappa-B, CARD-like apoptotic protein, caspase-recruiting domain-containing protein, CED-3/ICH-1 prodomain homologous E10-like regulator, Cellular homolog of vCARMEN, Cellular-E10 (cE10), CIPER, hCLAP, mE10, R-

Gene Name

BCL10

Gene ID

8915

UniProt

O95999

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant human BCL10 protein fragment (around aa122-168) (exact sequence is proprietary)

Clonality

Monoclonal

Clone

BL10/2988R

Applications

FACS, IF, IHC

Components

200 μg/mL of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/mL.

Storage Conditions

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.

Applications Notes

Flow Cytometry (1-2ug/million cells) ; Immunofluorescence (1-2ug/ml) ; , Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT), (Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 &degC followed by cooling at RT for 20 minutes)

Isotype

Rabbit IgG

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