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Anti-Calretinin / Calbindin 2 (Mesothelioma Marker) Monoclonal Antibody (Clone: CALB2/2807)

Selected Variant

36-3398-20

Size: 20 µg

It recognizes a protein of about 29kDa, which is identified as Calretinin (also known as Calbindin 2) . Calretinin is a vitamin D-dependent calcium-binding protein involved in calcium signaling. It is present in subsets of neurons throμghout the brain and spinal chord, including sensory ganglia. Antibody to calretinin is useful in differentiating mesothelioma from adenocarcinomas of the lung. It also aids in differentiating adrenal cortical neoplasms from pheochromocytomas.

Product Specifications

Product Name Alternative

29kDa calbindin; CAB29; CAL2; CALB2; Calbindin 2; Calbindin D29K; Calretinin; CR

Gene Name

CALB2

Gene ID

794

UniProt

P22676

Host

Mouse

Reactivity

Human

Immunogen

Recombinant human Calretinin (Calbindin 2) protein fragment (around aa23-242) (exact sequence is proprietary)

Clonality

Monoclonal

Clone

CALB2/2807

Applications

WB, IHC

Components

200 μg/mL of Ab Purified from rabbit anti-serum by Protein A. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA at 1.0mg/mL.

Storage Conditions

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.

Applications Notes

Western Blot (1-2ug/ml) ; Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT) (Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95&degC followed by cooling at RT for 20 minutes)

Isotype

Mouse IgG1, kappa

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