Anti-Tyrosinase-Related Protein-1 (TYRP-1) (Melanoma Marker) Polyclonal Antibody
It reacts with a 75kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1) . It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi.Recent evidence sμggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.
Product Specifications
Product Name Alternative
Gene Name
TYRP1
Gene ID
7306
UniProt
P17643
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant human TYRP1 protein
Clonality
Polyclonal
Applications
IHC
Components
200 μg/mL of Ab Purified by Protein A. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/mL.
Storage Conditions
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.
Applications Notes
Isotype
Rabbit IgG
Frequently Asked Questions
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