Anti-Tyrosinase-Related Protein-1 (TRP-1) (Melanoma Marker) Monoclonal Antibody (Clone: SPM456)
Selected Variant
36-3333-20
Size: 20 µg
It reacts with a 75kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1) . It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi.Recent evidence sμggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.
Product Specifications
Product Name Alternative
Gene Name
TYRP1
Gene ID
7306
UniProt
P17643
Host
Mouse
Reactivity
Human, Mouse
Immunogen
SK-MEL-23 cells
Clonality
Monoclonal
Clone
SPM456
Applications
FACS, IF
Components
Storage Conditions
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.
Applications Notes
Flow Cytometry (1-2ug/million cells) ; Immunofluorescence (1-2ug/ml)
Isotype
Mouse IgG2a, kappa
Price
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
CD11c (Dendritic Cell Marker) (ITGAX/1284), CF594 conjugate, 0.1mg/mL
GP2 (Glycoprotein 2) / ZAP75 (GP2/2569R), CF640R conjugate, 0.1mg/mL
Cytokeratin 20 (KRT20) (Colorectal Epithelial Marker) (KRT20/3145), Biotin conjugate, 0.1mg/mL
Cytokeratin, pan (Cocktail PAN-CK), CF488A conjugate, 0.1mg/mL
Prohibitin (Mitochondrial Marker) (PHB/3228), CF405S conjugate, 0.1mg/mL
