Anti-p73 (Tumor Suppressor) Monoclonal Antibody (Clone: P73/2531)
Selected Variant
36-3304-20
Size: 20 µg
The p53 gene is a widely studied anti-oncogene, or tumor suppressor gene. The p53 gene product can act as a negative regulator of cell growth in response to DNA damage. Mutations and allelic loss of the p53 gene have been associated with malignant transformation in a wide variety of human tumors. p53 shares considerable sequence similarity with p73, a gene that maps to a region in chromosome 1 that is frequently deleted in neuroblastomas. However, p73 does not appear to be activated by DNA damaging agents. The p73 isoform p73.
Product Specifications
Product Name Alternative
P53-like transcription factor; p53-related protein; p73; TP73; Tumor protein p73
Gene Name
TP73
Gene ID
7161
UniProt
O15350
Host
Mouse
Reactivity
Human
Immunogen
Recombinant full-length human TP73 protein
Clonality
Monoclonal
Clone
P73/2531
Applications
IHC
Components
Storage Conditions
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.
Applications Notes
Isotype
Mouse IgG2b, kappa
Price
Frequently Asked Questions
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