Anti-TIMP2 (Tissue Inhibitor of Metalloproteinase 2) Monoclonal Antibody (Clone: rTIMP2/2335)
Selected Variant
36-3262-20
Size: 20 µg
It recognizes a protein of 21kDa, identified as tissue inhibitor of metalloproteinases-2 (TIMP-2) . It is closely related to TIMP-1 and shows the highest binding affinity to both the latent (pro) and active forms of 72kDa Type IV collagenase (also known as MMP-2 or gelatinase A) . It also has affinity for the active form of 92kDa Type IV collagenase (also known as MMP-9 or gelatinase B) . TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.
Product Specifications
Product Name Alternative
Metalloproteinase inhibitor 2; TIMP metallopeptidase inhibitor 2; TIMP-2; TIMP2; Tissue Inhibitor of Metalloproteinase 2
Gene Name
TIMP2
Gene ID
7077
UniProt
P16035
Host
Mouse
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide from the N-terminus of human TIMP2 protein (aa56-66) (DSGNDIYGNPI)
Clonality
Monoclonal
Clone
RTIMP2/2335
Applications
IHC
Components
Storage Conditions
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.
Applications Notes
Isotype
Mouse IgG1, kappa
Price
Frequently Asked Questions
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