Anti-TGF-alphaalpha (Transforming Growth Factor alpha) Monoclonal Antibody (Clone: SPM357)
This antibody reacts with the C-terminus of TGF-alphaalpha and shows no cross-reaction with EGF and the neuropeptide synenkephalin. The staining with Ab-1 is completely blocked by the peptide used for raising this antibody. TGF-alpha (aa50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.
Product Specifications
Product Name Alternative
EGF-like TGF-alpha ETGF-alpha TFGA; TGF-alphaType 1; TGF-alpha; Wa1; Waved 1
Gene Name
TGF-alpha
Gene ID
7039
UniProt
P01135
Host
Mouse
Reactivity
Human, Rat, Mouse
Immunogen
A 17-amino acid synthetic peptide from the carboxyl-terminus of rat TGF-alpha.
Clonality
Monoclonal
Clone
SPM357
Applications
FACS, IF
Components
Storage Conditions
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.
Applications Notes
Flow Cytometry (1-2ug/million cells) ; Immunofluorescence (1-2ug/ml)
Isotype
Mouse IgG1, kappa
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