Anti-CD71 / Transferrin Receptor (TFRC) Monoclonal Antibody (Clone: 66IG10) -CF488
It recognizes a ~90-95kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190kDa. This MAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Its epitope is localized in the extracellular domain of CD71. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.
Product Specifications
Product Name Alternative
Mtvr-1, p90, TFR1, TFRC transferrin receptor (p90 CD71), TRFR
Gene Name
TFRC
Gene ID
7037
UniProt
P02786
Host
Mouse
Reactivity
Human
Immunogen
Human thymocytes (T-cells)
Clonality
Monoclonal
Clone
66IG10
Applications
FACS, IF
Components
Storage Conditions
Antibody with azide - store at 4 to 8°C. Antibody is stable for 24 months. Non-hazardous.
Applications Notes
Flow Cytometry (5ul per test per one million cells or 5ul per 100ul of whole blood) ; Immunofluorescence (1:50-1:100)
Isotype
Mouse IgG1, kappa
Conjugate
CF488
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