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Anti-MRP1 / ABCC1 (Multidrμg Resistance Related Protein 1) Monoclonal Antibody (Clone: MRP1/1344)

The two members of the large family of ABC transporters known to confer multidrμg resistance in human cancer cells are the MDR1 P-glycoprotein and the multidrμg-resistance protein MRP1. MRP1 is an integral membrane protein that contains an MDR-like core, an N-terminal membrane-bound region and a cytoplasmic linker, and it is expressed in various cerebral cells, as well as in lung, testis and peripheral blood.

Product Specifications

Product Name Alternative

ABC29; ABCC1; ATP binding cassette sub family C (CFTR/MRP) member 1; ATP-binding cassette sub-family C member 1; GSX; Leukotriene C (4) transporter; LTC4 transporter; Multidrμg resistance-associated protein 1 (MRP1)

Gene Name

ABCC1

Gene ID

4363

UniProt

P33527

Host

Mouse

Reactivity

Human

Immunogen

Recombinant full-length human ABCC1 protein

Clonality

Monoclonal

Clone

MRP1/1344

Applications

FACS, IF

Components

200 μg/mL of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/mL.

Storage Conditions

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.

Applications Notes

Flow Cytometry (1-2ug/million cells) ; Immunofluorescence (1-2ug/ml)

Isotype

Mouse IgG2a, kappa

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