Anti-MCAM (Melanoma Cell Adhesion Molecule) / MUC18 / CD146 Monoclonal Antibody (Clone: MCAM/3179)
Selected Variant
36-2746-100
Size: 100 µg
The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2+-independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. Mel-CAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease.
Product Specifications
Product Name Alternative
Gene Name
MCAM
Gene ID
4162
UniProt
P43121
Host
Mouse
Reactivity
Human
Immunogen
Recombinant human MCAM protein
Clonality
Monoclonal
Clone
MCAM/3179
Applications
ELISA
Components
Storage Conditions
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.
Applications Notes
ELISA (Use Ab at 2-4ug/ml for coating) (Order Ab without BSA)
Isotype
Mouse IgG2c, kappa
Price
Frequently Asked Questions
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