Anti-LMO2 (B-Cell Marker) Monoclonal Antibody (Clone: LMO2/3147R)
The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. It has a particular function in normal and lymphatic endothelial cells involving the regulation of angiogenesis and lymph-angiogenesis. Immunohistochemical studies have also demonstrated expression of LMO2 in both normal germinal center B-cells and germinal center-derived B-cell lymphomas, including follicular lymphoma and diffuse large B-cell lymphoma.The use of anti-LMO2 is valuable as a tool in the identification of lymphomas of B-cell origin. LMO2 is useful in differentiating follicular lymphoma (LMO2+) from nodal marginal zone lymphoma (LM02-) . It also is positive in Hodgkin s and Burkitt s lymphomas.
Product Specifications
Product Name Alternative
Gene Name
LMO2
Gene ID
4005
UniProt
P25791
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant fragment (around aa 23-140) human LMO2 protein (exact sequence is proprietary)
Clonality
Monoclonal
Clone
LMO2/3147R
Applications
FACS, IF
Components
Storage Conditions
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.
Applications Notes
Flow Cytometry (1-2ug/million cells) ; , Immunofluorescence (1-2ug/ml) ;
Isotype
Rabbit IgG
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