Anti-LMO2 (B-Cell Marker) Monoclonal Antibody (Clone: LMO2/1971)

The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. It has a particular function in normal and lymphatic endothelial cells involving the regulation of angiogenesis and lymph-angiogenesis. Immunohistochemical studies have also demonstrated expression of LMO2 in both normal germinal center B-cells and germinal center-derived B-cell lymphomas, including follicular lymphoma and diffuse large B-cell lymphoma.The use of anti-LMO2 is valuable as a tool in the identification of lymphomas of B-cell origin. LMO2 is useful in differentiating follicular lymphoma (LMO2+) from nodal marginal zone lymphoma (LM02-) . It also is positive in Hodgkin s and Burkitt s lymphomas.

Product Specifications

Product Name Alternative

Cysteine-rich protein TTG-2; LIM domain only protein 2; LMO-2; RBTN L1; RBTN2; Rhombotin like 1; Rhombotin-2 (RHOM2) ; T-cell translocation protein 2; TTG2

Gene Name

LMO2

Gene ID

4005

UniProt

P25791

Host

Mouse

Reactivity

Human

Immunogen

Recombinant human LMO2 protein fragment (around aa 23-140) (exact sequence is proprietary)

Clonality

Monoclonal

Clone

LMO2/1971

Applications

FACS, WB, IHC

Components

200 μg/mL of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/mL.

Storage Conditions

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.

Applications Notes

Flow Cytometry (1-2ug/million cells) ; Western Blot (1-2ug/ml) ; , Immunohistology (Formalin-fixed) (1-2ug/ml for 30 min at RT), (Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)