Anti-Arginase 1 (Hepatocellular Carcinoma Marker) Monoclonal Antibody (Clone: ARG1/1125)
Selected Variant
36-2645-20
Size: 20 µg
Recognizes a protein of 35-38kDa, which is identified as Arginase 1 (ARG1) . Arginase is a manganese metallo-enzyme that catalyzes the hydrolysis of arginine to generate ornithine and urea. Arginase I and II are isoenzymes which differ in subcellular localization, regulation, and possibly function. Arginase I is a cytosolic enzyme, which is expressed mainly in the liver as part of the urea cycle, whereas arginase II is a mitochondrial protein found in a variety of tissues. Antibody to ARG-1 labels hepatocytes in normal tissues and granulocytes in peripheral blood. ARG-1 is a sensitive and specific marker for identification of hepatocellular carcinoma.
Product Specifications
Product Name Alternative
Arginase 1; ARG1; liver-type arginase; type I arginase
Gene Name
ARG1
Gene ID
383
UniProt
P05089
Host
Mouse
Reactivity
Human
Immunogen
Recombinant human ARG1 protein fragment (around aa11-97) (exact sequence is proprietary)
Clonality
Monoclonal
Clone
ARG1/1125
Applications
WB, IHC
Components
Storage Conditions
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.
Applications Notes
Isotype
Mouse IgG3, kappa
Price
Frequently Asked Questions
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