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Anti-CD117 / c-Kit (Marker for Gastrointestinal Stromal Tumors) Monoclonal Antibody (Clone: KIT/2669)

Selected Variant

36-2644-20

Size: 20 µg

This MAb recognizes a protein of 145kDa, identified as CD117/p145kit. It is found on a wide variety of tumor cells including follicular and papillary carcinoma of thyroid, adenocarcinomas from endometrium, lung, ovary, pancreas, and breast as well as malignant melanoma, endodermal sinus tumor, and small cell carcinoma. However, anti-CD117 has been particularly useful in differentiating gastrointestinal stromal tumors from Kaposi's sarcoma, tumors of smooth muscle origin, fibromatosis, and neural tumors of the GI tract. Anti-CD117 is also useful in recognizing myeloblasts in bone marrow biopsy and clot section.

Product Specifications

Product Name Alternative

P145; Steel Factor Receptor; Stem Cell Factor Receptor (SCF-Receptor) ; Mast Cell Growth Factor Receptor

Gene Name

KIT

Gene ID

3815

UniProt

P10721

Host

Mouse

Reactivity

Human

Immunogen

Recombinant full-length human KIT protein

Clonality

Monoclonal

Clone

KIT/2669

Applications

ELISA

Components

200 μg/mL of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/mL.

Storage Conditions

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.

Applications Notes

ELISA (For coating, order antibody without BSA)

Isotype

Mouse IgG1, kappa

Price

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