Anti-VEGFR2 / CD309 / Flk-1 / KDR3 (Hemangioblast Marker) Monoclonal Antibody (Clone: KDR721)
Selected Variant
36-2638-100
Size: 100 µg
CD309, also known as VEGFR2, KDR3, and Flk-1 (Mouse), is a type I transmembrane glycoprotein. It is a member of the CSF-1/PDGF receptor family of type III tyrosine kinase receptors. Human VEGFR2 is mainly expressed by endothelial cells, embryonic tissues, and megakaryocytes. It plays an important role in the regulation of angiogenesis, vasculogenesis, and vascular permeability. The ligands of VEGFR2 include VEGF-A, VEGF-C, VEGF-D, and VEGF splice isoforms. Ligation of VEGFR2 with its ligands results in the receptor dimerization and auto-phosphorylation, stimulating endothelial cell proliferation and migration.
Product Specifications
Product Name Alternative
Gene Name
KDR
Gene ID
3791
UniProt
P35968
Host
Mouse
Reactivity
Human
Immunogen
Recombinant human VEGF-R2 protein
Clonality
Monoclonal
Clone
KDR721
Applications
FACS, IF, Functional Assay
Components
Storage Conditions
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.
Applications Notes
Flow Cytometry (1-2ug/million cells) ; Immunofluorescence (1-2ug/ml) ; Functional Studies (Order Ab without BSA & Azide)
Isotype
Mouse IgG1, kappa
Price
Frequently Asked Questions
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