Anti-CD41a / Integrin-b (Platelet Marker) Monoclonal Antibody (Clone: ITGA2B/1036)

Reacts with a calcium-dependent complex of CD41/CD61, a dimer of 90kDa and 140kDa present on the membrane of normal platelets and megakaryocytes. CD41/CD61 is also known as platelet glycoprotein GPIIb/GPIIIa or integrin IIa/ 3. This complex is the receptor of fibrinogen, fibronectin and von Willebrand factor, and mediates platelet adhesion and aggregation.

Product Specifications

Product Name Alternative

BDPLT16; BDPLT2; GPalpha IIb; GT; HPA3; Integrin alpha IIb; ITGA2B; ITGAB; platelet fibrinogen receptor, alpha subunit; platelet glycoprotein IIb of IIb/IIIa complex

Gene Name

ITGA2B

Gene ID

3674

UniProt

P08514

Host

Mouse

Reactivity

Human

Immunogen

Recombinant full-length human Integrin alpha IIb protein

Clonality

Monoclonal

Clone

ITGA2B/1036

Applications

FACS, IF

Components

200 μg/mL of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/mL.