Anti-Insulin-like Growth Factor-1 (IGF-1) Monoclonal Antibody (Clone: M23)
This antibody is specific to Insulin-like Growth Factor (IGF-1) and shows minimal cross-reaction with IGF-11, Proinsulin, MSF, and Insulin. IGF-1 is a polypeptide growth factor with two isoforms that are produced by alternative splicing. Isoform 1 is also known as IGF-IB while isoform 2 is known as IGF-IA. IGF-1 stimulates the proliferation of a wide range of cell types including muscle, bone and cartilage tissue. It functions as an autocrine regulator of growth. Activation of IGF system has emerged as a key factor for tumor progression and resistance to apoptosis in many cancers like those of breast, thyroid and colon.
Product Specifications
Product Name Alternative
Insulin-like Growth Factor IA (IGF-IA) ; Insulin-like Growth Factor IB (IGF-IB) ; Mechano Growth Factor (MGF) ; Somatomedin-C
Gene Name
IGF1
Gene ID
3479
UniProt
P05019
Host
Mouse
Reactivity
Human
Immunogen
Purified human IGF-1 protein
Clonality
Monoclonal
Clone
M23
Applications
FACS, IF
Components
Storage Conditions
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.
Applications Notes
Isotype
Mouse IgG1, kappa
Frequently Asked Questions
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