Anti-Interferon alpha-1 (IFNA1) Monoclonal Antibody (Clone: Feb-52)
This MAb is specific for human interferon alpha 1 and does not cross react with human interferon alpha 2. Interferons are widely used therapeutic agents because of their anti-tumor and anti-viral effects and because of their modulatory effects on the immune system. These cytokines produce their effects by binding to the Type 1 Interferon- Receptor (IFNAR1) . Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is influenced by phosphorylation of Serine 535 and 539 in the IFNAR1.
Product Specifications
Product Name Alternative
Gene Name
IFNA1
Gene ID
3439
UniProt
P01562
Host
Mouse
Reactivity
Human
Immunogen
Purified recombinant human IFN-alpha1
Clonality
Monoclonal
Clone
19025
Applications
FACS, IF
Components
Storage Conditions
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.
Applications Notes
Flow Cytometry (0.5-1ug/million cells) ; , Immunofluorescence (0.5-1ug/ml) ;
Isotype
Mouse IgG1, kappa
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