Anti-Interferon alpha-1 (IFNA1) Monoclonal Antibody (Clone: Feb-48)

This MAb is specific for human interferon alpha 1 and does not cross react with human interferon alpha 2. Interferons are widely used therapeutic agents because of their anti-tumor and anti-viral effects and because of their modulatory effects on the immune system. These cytokines produce their effects by binding to the Type 1 Interferon- Receptor (IFNAR1) . Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is influenced by phosphorylation of Serine 535 and 539 in the IFNAR1.

Product Specifications

Product Name Alternative

IFN alpha; IFN alpha 1/13; IFN alpha 1b; Interferon alpha 13 (IFNA13) ; Interferon alpha leukocyte (IFL) ; Interferon alpha-1/13 (IFN-alpha-1/13) ; Interferon alpha-D (IFN alphaD) ; Interferon alpha1 (IFNA1) ; LeIF D

Gene Name

IFNA1

Gene ID

3439

UniProt

P01562

Host

Mouse

Reactivity

Human

Immunogen

Purified recombinant human IFN-alpha1

Clonality

Monoclonal

Clone

17564

Applications

FACS, WB, IHC, IF

Components

200 μg/mL of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/mL.