Anti-CD50 / ICAM3 Monoclonal Antibody (Clone: CG106)
Recognizes the D1 domain of an N-glycosylated glycoprotein of 120kDa with intra-chain disulfide bonds, identified as CD50 or ICAM-3 (Leucocyte Workshop VI) . CD50 is the major ligand for LFA-1 (CD11a/CD18) and may have signaling role to increase adhesion. It is expressed on thymocytes and T lymphocytes and is resistant to treatment with phosphatidylinositol (PI) phospholipase C. This MAb is excellent for staining of formalin/paraffin tissues.
Product Specifications
Product Name Alternative
CD50; CDW 50; CDw50; ICAM 3; ICAM-3; ICAM-R; ICAM3; ICAM3_HUMAN; ICAMR; Intercellular adhesion molecule 3
Gene Name
ICAM3
Gene ID
3385
UniProt
P32942
Host
Mouse
Reactivity
Human
Immunogen
Stimulated human leukocytes
Clonality
Monoclonal
Clone
CG106
Applications
FACS, IF
Components
Storage Conditions
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.
Applications Notes
Blocks binding of CD11a (LFA-1) to CD50 (ICAM-3) (Order Ab without Azide) ; Flow Cytometry (1-2ug/million cells) ; Immunofluorescence (1-2ug/ml)
Isotype
Mouse IgG2a, kappa
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
