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Anti-CD50 / ICAM3 Monoclonal Antibody (Clone: ICO-60)

Recognizes the N-glycosylated glycoprotein of 120kDa with intra-chain disulfide bonds, identified as CD50 or ICAM-3. CD50 is the major ligand for LFA-1 (CD11a/CD18) and may have signaling role to increase adhesion. It is expressed on thymocytes and T lymphocytes and is resistant to treatment with phosphatidylinositol (PI) phospholipase C.

Product Specifications

Product Name Alternative

ICAMR; Intercellular adhesion molecule 3 (ICAM3)

Gene Name

ICAM3

Gene ID

3385

UniProt

P32942

Host

Mouse

Reactivity

Human

Immunogen

Human ICAM3

Clonality

Monoclonal

Clone

ICO-60

Applications

FACS, IF

Components

200 μg/mL of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/mL.

Storage Conditions

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.

Applications Notes

Flow Cytometry (1-2ug/million cells) ; Immunofluorescence (1-2ug/ml)

Isotype

Mouse IgG1, kappa

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