Anti-HLA-DP (MHC II) Monoclonal Antibody (Clone: SPM421)
Recognizes a non-polymorphic determinant of DP-MHC class II. MHC class II antigens are transmembrane glycoproteins of non-covalently linked alpha (33-35kDa) and beta (27-30kDa) chains. It reportedly reacts with B- non-T, non-B cell lines but not with T- and myeloid cell lines and leukemias. Differential expression of MHC class II antigens on fetal and adult lymphocytes, malignant B cells appears to reflect the stage of cell differentiation which may be useful in the study of lymphoproliferative disorders.
Product Specifications
Product Name Alternative
Gene Name
HLA-DPB1
Gene ID
3115
UniProt
P04440
Host
Mouse
Reactivity
Human
Immunogen
Non-T, non-B human acute lymphoblastic leukemia REH6 cell line
Clonality
Monoclonal
Clone
SPM421
Applications
ELISA, FACS, IF
Components
Storage Conditions
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.
Applications Notes
ELISA (For coating, order antibody without BSA) ; Flow Cytometry (1-2ug/million cells) ; Immunofluorescence (1-2ug/ml)
Isotype
Mouse IgG2b, kappa
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