Anti-HLA-ABC (MHC I) Monoclonal Antibody (Clone: 246-B8.E7)
Reacts with a monomorphic determinant of human major histocompatibility (MHC) class I antigens (HLA-A, B and C) . Human MHC class I antigens are expressed constitutively on all nucleated cells lymphocytes such as lymphocytes, thymocytes, granulocytes, and bone marrow cells and are absent on erythrocytes. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation.
Product Specifications
Product Name Alternative
Gene Name
HLA-A; HLA-B; HLA-C
Gene ID
3105; 3106; 3107
UniProt
P01889; P30443; P30499
Host
Mouse
Reactivity
Human, Mouse
Immunogen
Human peripheral blood leukocytes
Clonality
Monoclonal
Clone
246-B8.E7
Applications
FACS, IF
Components
Storage Conditions
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.
Applications Notes
Flow Cytometry (1-2ug/million cells) ; Immunofluorescence (1-2ug/ml)
Isotype
Mouse IgG2a, kappa
Frequently Asked Questions
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