Anti-Annexin A1 / (Hairy Cell Leukemia Marker) Monoclonal Antibody (Clone: ANXA1/1672)
Selected Variant
36-2459-20
Size: 20 µg
The ANXA1 gene belongs to the annexin family, and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. ANXA1 promotes membrane fusion and is involved in exocytosis. The gene for ANXA1 is upregulated in hairy cell leukemia (HCL), and its protein expression is specific for HCL. Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, sμggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance.
Product Specifications
Product Name Alternative
ANXA1; ANX1; Annexin-1; Chromobindin-9; LPC1; p35
Gene Name
ANXA1
Gene ID
301
UniProt
P04083
Host
Mouse
Reactivity
Human
Immunogen
Recombinant full-length human Annexin A1 protein
Clonality
Monoclonal
Clone
ANXA1/1672
Applications
FACS, WB, ELISA
Components
Storage Conditions
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.
Applications Notes
Flow Cytometry (1-2ug/million cells) ; Western Blot (1-2ug/ml) ; ELISA (Use Ab at 2-4ug/ml for coating) (Order Ab without BSA)
Isotype
Mouse IgG1, kappa
Price
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