Anti-PD-L1 / PDCD1LG1 / CD274 / B7-H1 (Cancer Immunotherapy Target) Monoclonal Antibody (Clone: PDL1/2743)
Selected Variant
36-2428-20
Size: 20 µg
PD-L1 is a checkpoint regulator in immune cells, it is expressed on immune or non-hematopoietic cells. Expression of the protein is seen during pregnancy where it has a role in suppressing the immune system. PD-L1 induces an inhibitory signal in activated T-cells and promotes T-cell apoptosis. It is overexpressed in a number of different cancers where it is believed to play a significant role in the cancer s ability to evade the immune system.
Product Specifications
Product Name Alternative
B7 homolog 1; B7-H1; CD274; PD-L1; PDCD1 ligand 1; PDCD1L1; PDCD1LG1; Programmed cell death 1 ligand 1
Gene Name
CD274
Gene ID
29126
UniProt
Q9NZQ7
Host
Mouse
Reactivity
Human
Immunogen
Recombinant fragment of human CD274 protein (around aa 39-191) (exact sequence is proprietary)
Clonality
Monoclonal
Clone
PDL1/2743
Applications
ELISA, FACS, IF
Components
Storage Conditions
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.
Applications Notes
ELISA (For coating, order antibody without BSA) ; , Flow Cytometry (1-2ug/ml) ; , Immunofluorescence (1-2ug/ml) ;
Isotype
Mouse IgG2b, kappa
Price
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
GP2 (Glycoprotein 2) / ZAP75 (GP2/1805), CF640R conjugate, 0.1mg/mL
Testosterone (4E1G2), CF555 conjugate, 0.1mg/mL
CD4 (T-Helper/Inducer Cell Marker) (RIV7), CF568 conjugate, 0.1mg/mL
