Anti-MART-1 / Melan-A / MLANA (Melanoma Marker) Monoclonal Antibody (Clone: MLANA/1761R)
Selected Variant
36-2299-20
Size: 20 µg
This antibody recognizes a protein doublet of 20-22kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This MAb labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.
Product Specifications
Product Name Alternative
Antigen LB39-AA, Antigen SK29-AA, Melanoma antigen recognized by T-cells 1, MLAN-A, MLANA
Gene Name
MLANA
Gene ID
2315
UniProt
Q16655
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant human full-length MLANA protein
Clonality
Monoclonal
Clone
MLANA/1761R
Applications
WB, IHC
Components
200 μg/mL of Ab Purified by Protein A. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/mL.
Storage Conditions
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.
Applications Notes
Isotype
Rabbit IgG
Price
Frequently Asked Questions
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