Anti-Estrogen Receptor, alpha (Marker of Estrogen Dependence) Monoclonal Antibody (Clone: ER506) -CF488
Selected Variant
36-2249-0.5
Size: 0.5 mL (100 μg/mL)
This MAb is specific to ER alpha and shows minimal cross-reaction with other members of the family. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy. It strongly stains nuclei of epithelial cells in breast carcinomas.
Product Specifications
Product Name Alternative
Estrogen Receptor alpha delta 4*5,6,7*/654 isoform; Estrogen Receptor alpha delta 4 +49 isoform; Nuclear receptor subfamily 3 group A member 1
Gene Name
ESR1
Gene ID
2099
UniProt
P03372
Host
Mouse
Reactivity
Human
Immunogen
Recombinant human Estrogen Receptor alpha protein (aa2-185)
Clonality
Monoclonal
Clone
ER506
Applications
FACS, IF
Components
Storage Conditions
Antibody with azide - store at 4 to 8°C. Antibody is stable for 24 months. Non-hazardous.
Applications Notes
Flow Cytometry (5ul per test per one million cells or 5ul per 100ul of whole blood) ; , Immunofluorescence (1:50-1:100) ;
Isotype
Mouse IgG1, kappa
Conjugate
CF488
Price
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