Anti-EGFR (Epidermal Growth Factor Receptor) Monoclonal Antibody (Clone: B1D8)
This antibody reacts with the extracellular domain of EGFR and blocks the EGF/TGF-alphainduced activation. It also blocks tumor growth in vivo. It is excellent for purification of EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-alphaa), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin.
Product Specifications
Product Name Alternative
Erbb1; ERBB1; Errp; HER1; mENA; PIG61; Proto-oncogene c-ErbB-1; Receptor Tyrosine Protein Kinase; ErbB1; Urogastrone; wa2; Wa5
Gene Name
EGFR
Gene ID
1956
UniProt
P00533
Host
Mouse
Reactivity
Human
Immunogen
Microsomes from A431 cells.
Clonality
Monoclonal
Clone
B1D8
Applications
IP, FACS
Components
Storage Conditions
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.
Applications Notes
Isotype
Mouse IgG2a, kappa
Frequently Asked Questions
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