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Anti-Clathrin, Heavy Chain Monoclonal Antibody (Clone: CHC/1432)

Recognizes protein of 192kDa, which is identified as Clathrin Heavy Chain. Clathrin is composed of three heavy chains and three light chains, which associate non-covalently to form a triskelion structure. Clathrin heavy chain (HC) is composed of a terminal globular domain, a distal segment and a proximal segment containing a light chain-binding site. The proximal segment of the Clathrin HC protein is essential for interactions between Clathrin heavy chains and light chains, which result in the formation of the triskelion structure.

Product Specifications

Product Name Alternative

Clathrin heavy chain; Clathrin heavy chain 1; Clathrin heavy chain 2; Clathrin heavy chain on chromosome 17 (CHC17 or CHC-17) ; CLH22; CLTC; CLTCL; CLTCL1; CLTCL2; CLTD

Gene Name

CLTC

Gene ID

1213

UniProt

P53675; Q00610

Host

Mouse

Reactivity

Mouse, Rat, Human

Immunogen

Recombinant full-length human Clathrin Heavy Chain protein

Clonality

Monoclonal

Clone

CHC/1432

Applications

IF

Components

200μg/mL of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/mL.

Storage Conditions

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months.

Applications Notes

Immunofluorescence (1-2ug/ml)

Isotype

Mouse IgG1, kappa

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