Polyclonal Antibody to p40 (deltaNp63) (Squamous, Basal & Myoepithelial Cell Marker)
P40 (p63 delta) is a marker recently determined to be highly specific for squamous basal cells in the immunohistochemistry (IHC) application. The current more routinely recommended marker, p63, appears to have less specificity compared to p40, especially on squamous cell tumors. The ability to differentiate between lung adenocarcinoma vs. squamous cell carcinoma is difficult and has bearing on the different therapeutic avenues for each subtype treatment. p63 antibody's ability to distinguish between the tumor types appears to be inferior when compared to p40. The ability to utilize an antibody probe for p40 as a squamous cell marker bolsters its use for future sub-classification of lung cancers, especially by immunohistochemical techniques.
Product Specifications
Product Name Alternative
TP63||KET||P63||P73H||P73L||TP73L
Gene Name
TP63
Gene ID
8626
UniProt
Q9H3D4
Host
Rabbit
Reactivity
Rat, Mouse, Human
Immunogen
A synthetic peptide (ENNAQTQFSEPQY) corresponding to aa5-17 of human p40
Target Antigen
P40 (deltaNp63) (Squamous, Basal & Myoepithelial Cell Marker)
Clonality
Polyclonal
Applications
WB, IHC
Purification
Affinity Chromatography
Format
Purified
Components
100 μg in 500 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Isotype
Rabbit IgG
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items