Polyclonal Antibody to Uroplakin 3A (Bladder Carcinoma Marker)
Uroplakin-3A (UPK3A) is a component of the asymmetric unit membrane (AUM) . It is a highly specialized bio-membrane made by terminally differentiated urothelial cells. The protein may play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. UPK3A also contributes to the formation of urothelial glycocalyx, which may play an important role in preventing bacterial adherence through FimH bacterial protein binding leading to bladder infection. UPK3A has been shown as a helpful marker for the detection of bladder cancer.
Product Specifications
Product Name Alternative
UPK3A||UPK3
Gene Name
UPK3A
Gene ID
7380
UniProt
O75631
Host
Rat
Reactivity
Human
Immunogen
A synthetic peptide, aa260-279 (GASESSYTSVNRGPPLDRAE) of human UPK3A
Target Antigen
Uroplakin 3A (Bladder Carcinoma Marker)
Clonality
Polyclonal
Applications
WB
Purification
Affinity Chromatography
Format
Purified
Components
100 μg in 500 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Western Blot (1-2ug/ml)
Isotype
Rabbit IgG
Frequently Asked Questions
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