Monoclonal Antibody to Tyrosinase-Related Protein-1 (TYRP-1) (Melanoma Marker) (Clone : SPM611)
Selected Variant
36-1783-100
Size: 100 µg
It reacts with a 75kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1) . It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi. Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.
Product Specifications
Product Name Alternative
TYRP1||CAS2||TYRP||TYRRP
Gene Name
TYRP1
Gene ID
7306
UniProt
P17643
Host
Mouse
Reactivity
Human, Mouse
Immunogen
Recombinant full-length human TYRP1 protein
Target Antigen
Tyrosinase-Related Protein-1 (TYRP-1) (Melanoma Marker)
Clonality
Monoclonal
Clone
SPM611
Applications
FACS, IF, IHC
Purification
Affinity Chromatography
Format
Purified
Components
100 μg in 500 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Isotype
Mouse IgG2a, kappa
Price
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Anti-Protein Wnt-2b Wnt2b Antibody Picoband®, APC Conjugate
14-3-3 Sigma / Stratifin (CPTC-SFN-2), CF488A conjugate, 0.1mg/mL
Cytokeratin 10 (Suprabasal Epithelial Marker) (rKRT10/1275), CF640R conjugate, 0.1mg/mL
