Monoclonal Antibody to GRP94 / HSP90B1 (Endoplasmic Reticulum Marker) (Clone : 9G10.F8.2)
Recognizes a protein of 94kDa, which is identified as the glucose-regulated protein 94 (grp94) and also tumor rejection antigen (gp96) . Grp94 shows a high degree of sequence homology with the heat shock protein 90 (hsp90) . This MAb is highly specific to grp94 and shows minimal cross-reaction with other members of the HSP90 family. Grp s are a class of proteins unresponsive to heat shock and are induced by glucose deprivation. Grp94 has been briefly studied as a prognostic factor in breast cancer.
Product Specifications
Product Name Alternative
HSP90B1||GRP94||TRA1
Gene Name
HSP90B1
Gene ID
7184
UniProt
P14625
Host
Rat
Reactivity
Human, Rat, Mouse, Hamster
Immunogen
Purified glucose regulated protein 94 (grp94) from chicken oviducts
Target Antigen
GRP94 / HSP90B1 (Endoplasmic Reticulum Marker)
Clonality
Monoclonal
Clone
9G10.F8.2
Applications
FACS, IF, WB, IHC
Purification
Affinity Chromatography
Format
Purified
Components
100 μg in 500 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Isotype
Rat IgG2a, kappa
Frequently Asked Questions
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