Monoclonal Antibody to gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (Clone : SPM286)
Selected Variant
36-1681-100
Size: 100 µg
By immunohistochemistry, it specifically recognizes a protein in melanocytes and melanomas. This MAb reacts with junctional and blue nevus cells and variably with fetal and neonatal melanocytes. Intradermal nevi, normal adult melanocytes, and non-melanocytic cells are negative. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.This Mab labels formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.
Product Specifications
Product Name Alternative
PMEL||D12S53E||PMEL17||SILV
Gene Name
PMEL
Gene ID
6490
UniProt
P40967
Host
Mouse
Reactivity
Human
Immunogen
Membranes from a human melanoma metastasis
Target Antigen
Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker)
Clonality
Monoclonal
Clone
SPM286
Applications
FACS, IF, IHC
Purification
Affinity Chromatography
Format
Purified
Components
100 μg in 500 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Isotype
Mouse IgG2b, kappa
Price
Frequently Asked Questions
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