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Monoclonal Antibody to gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (Clone : NKI-beteb)

Selected Variant

36-1680-100

Size: 100 µg

By immunohistochemistry, it specifically recognizes a protein in melanocytes and melanomas. This MAb reacts with junctional and blue nevus cells and variably with fetal and neonatal melanocytes. Intradermal nevi, normal adult melanocytes, and non-melanocytic cells are negative. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.This Mab labels formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.

Product Specifications

Product Name Alternative

PMEL||D12S53E||PMEL17||SILV

Gene Name

PMEL

Gene ID

6490

UniProt

P40967

Host

Mouse

Reactivity

Human

Immunogen

Membranes from a human melanoma metastasis

Target Antigen

Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker)

Clonality

Monoclonal

Clone

NKI-beteb

Applications

IHC

Purification

Affinity Chromatography

Format

Purified

Components

100 μg in 500 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.

Storage Conditions

Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.

Applications Notes

Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT), (Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95&degC followed by cooling at RT for 20 minutes)

Isotype

Mouse IgG2b, kappa

Price

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