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Monoclonal Antibody to Retinol Binding Protein-1 (RBP1) (Clone : RBP/872)

Recognizes a protein of 21kDa-25kDa, identified as retinol binding protein-1 (RBP1) . This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein post-transnationally and results in defective delivery and supply to the epidermal cells.

Product Specifications

Product Name Alternative

RBP4||PRO2222

Gene Name

RBP4

Gene ID

5950

UniProt

P02753

Host

Mouse

Reactivity

Human, Rat, Mouse

Immunogen

Recombinant human retinol binding protein-1 (RBP1)

Target Antigen

Retinol Binding Protein-1 (RBP1)

Clonality

Monoclonal

Clone

RBP/872

Applications

IHC

Purification

Affinity Chromatography

Format

Purified

Components

100 μg in 500 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.

Storage Conditions

Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.

Applications Notes

Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT) (Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95&degC followed by cooling at RT for 20 minutes)

Isotype

Mouse IgG1, kappa

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