Monoclonal Antibody to Bax (Apoptosis Marker) (Clone : BAX/962)
Recognizes a protein of 21kDa, identified as the Bax protein. This MAb is highly specific to Bax and shows no cross-reaction with Bcl-2 or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and Bax also counters the death repressor activity of Bcl-2.
Product Specifications
Product Name Alternative
BAX||BCL2L4
Gene Name
BAX
Gene ID
581
UniProt
Q07812
Host
Mouse
Reactivity
Human
Immunogen
Recombinant full-length human BAX protein.
Target Antigen
Bax (Apoptosis Marker)
Clonality
Monoclonal
Clone
BAX/962
Applications
FACS, IHC
Purification
Affinity Chromatography
Format
Purified
Components
100 μg in 500 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Isotype
Mouse IgG1, kappa
Frequently Asked Questions
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