Monoclonal Antibody to Prolactin Receptor (hPRL-Receptor) (B6.2 + PRLR742)

It recognizes a protein of 70kDa, identified as prolactin receptor. Prolactin is a pituitary hormone involved in the stimulation of milk production, salt and water regulation, growth, development and reproduction. The initial step in its action is the binding to a specific membrane receptor (prolactin receptor), which belongs to the superfamily of class 1 cytokine receptors. The function of the prolactin receptor is mediated, at least in part, by two families of signaling molecules: Janus kinases and signal transducers and activators of transcription.

Product Specifications

Product Name Alternative

PRLR

Gene Name

PRLR

Gene ID

5618

UniProt

P16471

Host

Mouse

Reactivity

Human

Immunogen

Semi-purified human prolactin receptor (B6.2) ; Recombinant human prolactin receptor (PRLR742)

Target Antigen

Prolactin Receptor (hPRL-Receptor)

Clonality

Monoclonal

Clone

B6.2 + PRLR742

Applications

IHC

Purification

Affinity Chromatography

Format

Purified

Components

100 μg in 500 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.

Storage Conditions

Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.

Applications Notes

Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT) (Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95&degC followed by cooling at RT for 20 minutes)