Monoclonal Antibody to Prolactin Receptor (hPRL-Receptor) (Clone : SPM213)

It recognizes a protein of 70kDa, identified as prolactin receptor. Prolactin is a pituitary hormone involved in the stimulation of milk production, salt and water regulation, growth, development and reproduction. The initial step in its action is the binding to a specific membrane receptor (prolactin receptor), which belongs to the superfamily of class 1 cytokine receptors. The function of the prolactin receptor is mediated, at least in part, by two families of signaling molecules: Janus kinases and signal transducers and activators of transcription.

Product Specifications

Product Name Alternative

PRLR

Gene Name

PRLR

Gene ID

5618

UniProt

P16471

Host

Mouse

Reactivity

Human

Immunogen

Semi-purified human prolactin receptor

Target Antigen

Prolactin Receptor (hPRL-Receptor)

Clonality

Monoclonal

Clone

SPM213

Applications

FACS, IF, IHC

Purification

Affinity Chromatography

Format

Purified

Components

100 μg in 500 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.

Storage Conditions

Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.

Applications Notes

Flow Cytometry (0.5-1ug/million cells) ; Immunofluorescence (0.5-1ug/ml) ; , Immunohistology (Formalin-fixed) (0.5-1ug/ml for 30 minutes at RT), (Staining of formalin/paraffin tissues requires digestion of tissue sections with pepsin at 1mg/ml Tris-HCl, pH 2.0 for 15 min at RT or 10 min at 37C.)