Monoclonal Antibody to Podocalyxin (PODXL) (Hematopoietic Stem Cell Marker) (Clone : 3D3)
Podocalyxin is a member of the CD34 transmembrane sialomucin family. It is over-expressed on the podocyte foot projections and plays essential roles in kidney development and homeostasis, blood filtration and urine formation. It is also expressed on vascular endothelia, hematopoietic progenitors and a subset of neurons. Overexpression of podocalyxin may be linked to more aggressive tumor behavior. Podocalyxin antibody can identify podocytes in the urine (podocyturia) that may indicate glomerular disease, pre-eclampsia, and other kidney pathology.
Product Specifications
Product Name Alternative
PODXL||PCLP||PCLP1
Gene Name
PODXL
Gene ID
5420
UniProt
O00592
Host
Mouse
Reactivity
Human, Rat
Immunogen
A recombinant protein fragment containing the intracellular, transmembrane, and part of the extracellular domain of human podocalyxin
Target Antigen
Podocalyxin (PODXL) (Hematopoietic Stem Cell Marker)
Clonality
Monoclonal
Clone
3D3
Applications
FACS, IF, IP, WB, IHC
Purification
Affinity Chromatography
Format
Purified
Components
100 μg in 500 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Isotype
Mouse IgG1, kappa
Frequently Asked Questions
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